{"id":3634160,"date":"2023-12-01T15:21:33","date_gmt":"2023-12-01T20:21:33","guid":{"rendered":"https:\/\/vip2-msd.com\/merckcom-migrated\/?page_id=3634160"},"modified":"2024-04-16T12:05:17","modified_gmt":"2024-04-16T16:05:17","slug":"the-journey-of-a-molecule","status":"publish","type":"page","link":"https:\/\/vip2-msd.com\/merckcom-migrated\/what-we-do\/the-journey-of-a-molecule\/","title":{"rendered":"The journey of a molecule"},"content":{"rendered":"\n<div id=\"mco-b2-hero-block-block_1254310726794e5a919b043fc09e74df\" class=\"mco-b2-hero-block full mccberg-block\">\n    <div class=\"mco-b2-hero-block-wrapper\">\n        <div class=\"mco-b2-hero-block-image-section \">\n\n                            <div class=\"mco-b2-hero-block-image-container \">\n                    <picture >\n\t<source media=\"(max-width: 767px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=768\" srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=768\" >\n<source media=\"(min-width: 768px) and (max-width: 1199px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?h=768\" srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?h=768\" >\n<source media=\"(min-width: 1200px) and (max-width: 1919px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=1200\" srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=1200\" >\n<source media=\"(min-width: 1920px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=1920\" srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=1920\" >\n\t<img data-src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/spot_discovery-looking-out-on-world-blue_hi_300dpi-1.jpg?w=1920\" alt=\"person wearing white lab coat looking out of a door into world full of molecules\" class=\"eager \" loading=\"eager\" \/>\n<\/picture>                                    <\/div>\n                        <div class=\"mco-b2-hero-block-image-container-two\">\n                            <\/div>\n        <\/div>\n\n        <div class=\"mco-b2-hero-block-content-section\">\n            <nav class=\"breadcrumbs wrapper text-descriptive\"aria-label=\"Breadcrumbs\"><\/nav>            \n                            <h1>The journey of a molecule<\/h1>\n            \n                            <div class=\"mco-b2-hero-block-description\"><p>Creating a medicine or vaccine is a journey &#8212; from the lab to patients.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"block-6c2ae5a7-d1e6-4950-aaae-b5bdb84a46c3\" class=\"block-editor-rich-text__editable block-editor-block-list__block wp-block is-selected wp-block-heading rich-text\" role=\"document\" aria-label=\"Block: Heading\" data-block=\"6c2ae5a7-d1e6-4950-aaae-b5bdb84a46c3\" data-type=\"core\/heading\" data-title=\"Heading\"><\/h2>\n<h2 id=\"block-6c2ae5a7-d1e6-4950-aaae-b5bdb84a46c3\" class=\"block-editor-rich-text__editable block-editor-block-list__block wp-block is-selected wp-block-heading rich-text\" role=\"document\" aria-label=\"Block: Heading\" data-block=\"6c2ae5a7-d1e6-4950-aaae-b5bdb84a46c3\" data-type=\"core\/heading\" data-title=\"Heading\"><\/h2>\n<p>&nbsp;<\/p>\n<\/div>\n            \n                    <\/div>\n    <\/div>\n\n    \n<\/div>\n\n\n<div id=\"mco-title-block-block_e5fa440808621062ba579d5df84e9513\" \n\t class=\"mco-title-block mccberg-block aligncenter has-background full negative\" \n\t style='background-image: url(https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/10\/MicrosoftTeams-image-126.png?w=1600);'\t >\n\t<div class=\"wrapper\">\n\t\t<div class=\"mco-title-block-content\">\n\t\t\t\n\t\t\t<h2 class=\"mco-title-block-title\">Moving from molecule to market requires innovation, expertise, tenacity and agility<\/h2>\n\n\t\t\t\t\t\t\t<p class=\"mco-title-block-description\"><p style=\"text-align: center\">It includes the work of many people &#8212; from scientists, data analysts and clinical trial volunteers to manufacturing, regulatory, development, marketing and commercial teams, among many others.<\/p>\n<\/p>\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n    <section id=\"mco-article-slideshow-block_8336b6549f21b22471da6c080f0b4726\" class=\"mco-article-slideshow full mccberg-block mt-2 mb-2\" data-images=12>\n        <div class=\"mco-article-slideshow-container\">\n            <div class=\"mco-article-slideshow-image-slider-container\">\n                <span class=\"mco-article-slideshow-expand-toggle\">\n                    <span class=\"mco-article-slideshow-expand\">\n                        <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"nonzero\" d=\"M3 7.172v5.656h5.657v2H1V7.172h2zM14.828 1v7.657h-2V3L7.172 3V1h7.656z\" \/>\n<title>Resize icon<\/title><\/svg>\n                    <\/span>\n                    <span class=\"mco-article-slideshow-close\">\n                        <svg 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data-src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/11\/JoM_Slides_05_Commercialization.jpg?resize=1238\"\n                                    alt=\"\"\n                                    class=\"lazyload\"\n                                    loading=\"lazy\"\n                                \/>\n                            <\/picture>\n                        <\/li>\n                                                                    <li>\n                            <picture>\n                                <source media=\"(min-width: 768px) and (max-width: 1199px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/11\/JoM_Slides_05_Commercialization_SimpleFact.jpg?resize=768\">\n                                <source media=\"(min-width: 1200px)\" data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/11\/JoM_Slides_05_Commercialization_SimpleFact.jpg?resize=1238\">\n                                <img\n                                    data-src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/11\/JoM_Slides_05_Commercialization_SimpleFact.jpg?resize=1238\"\n                                    alt=\"commercialization fact\"\n                                    class=\"lazyload\"\n                                    loading=\"lazy\"\n                                \/>\n                            <\/picture>\n                        <\/li>\n                                                                    <li>\n                            <picture>\n                                <source media=\"(min-width: 768px) and (max-width: 1199px)\" 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d=\"M8.5,16.5a8,8,0,1,1,8-8A8.009,8.009,0,0,1,8.5,16.5Z\" \/>\n\t<image class=\"btn-previous-icon\" x=\"5\" y=\"4\" width=\"6\" height=\"10\" xlink:href=\"\/wp-content\/themes\/cex-wpvip-mhh-mhh2-mcc-theme\/images\/arrow-left.svg\" \/>\n\t<image class=\"btn-previous-icon-hover\" x=\"5\" y=\"4\" width=\"6\" height=\"10\" xlink:href=\"\/wp-content\/themes\/cex-wpvip-mhh-mhh2-mcc-theme\/images\/arrow-left-white.svg\" \/>\n<\/svg>\n                            <\/div>\n                            <div class=\"btn-next\">\n                                <svg class=\"btn-next-wrapper\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 17 17\">\n\t<title>Next<\/title>\n\t<path class=\"btn-next-meter\" d=\"M8.5,16.5a8,8,0,1,1,8-8A8.009,8.009,0,0,1,8.5,16.5Z\" \/>\n\t<path class=\"btn-next-progress\" d=\"M8.5,16.5a8,8,0,1,1,8-8A8.009,8.009,0,0,1,8.5,16.5Z\" \/>\n\t<image class=\"btn-next-icon\" x=\"6\" y=\"4\" width=\"6\" height=\"10\" xlink:href=\"\/wp-content\/themes\/cex-wpvip-mhh-mhh2-mcc-theme\/images\/arrow-right.svg\" \/>\n\t<image class=\"btn-next-icon-hover\" x=\"6\" y=\"4\" width=\"6\" height=\"10\" xlink:href=\"\/wp-content\/themes\/cex-wpvip-mhh-mhh2-mcc-theme\/images\/arrow-right-white.svg\" \/>\n<\/svg>\n                            <\/div>\n                        <\/div>\n                    <\/div>\n                                <div class=\"mco-article-slideshow-info-slider-container\">\n                    <ul class=\"mco-article-slideshow-info-slider\">\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Discovery is the process of exploring new and unique molecules, compounds and biologics that may have the potential to treat or prevent disease. We consider variables such as disease prevalence, unmet medical needs and current treatment options when identifying a preclinical candidate (PCC).<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">  It takes about 10 years for a new product to reach the marketplace after the initial discovery.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">During this phase, the active pharmaceutical ingredient is produced to create the material that will be supplied for the clinical studies.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">1 in every 5,000 compounds that enter discovery and progress to preclinical development actually become an approved drug.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Clinical studies determine the safety and efficacy of our products by gathering evidence through testing and analysis in trial volunteers \u2014 first in healthy volunteers, then in those with the disease. Once we have sufficient safety and efficacy data, we file an application with the information we know about the product \u2014 including study data, analyses and reports \u2014 with a regulatory agency (such as the U.S. Food and Drug Administration) for approval.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Less than 12% of investigational medicines that enter clinical testing make it to approval.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Manufacturing is the process of industrial-scale production, packaging and distribution of our medicines and vaccines. The process varies from product to product but is always in full compliance with all regulations and Good Manufacturing Practices (GMPs, also referred to as &quot;cGMPs&quot; or &quot;current GMPs&quot;) to ensure a compliant, reliable supply for our patients.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">GMP regulations outline the minimum quality standards for manufacturing and vary by country. Each country has its own agency to monitor meeting the regulations and requirements.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Once a product is approved and manufactured, we promote it \u2014  through education and awareness campaigns \u2014  to customers, including physicians, health care providers, pharmacies, patient populations, wholesalers and governments. With a customer- and data-focused approach, we develop a brand strategy to create a unique impression for each product.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Marketing teams are key to creating the campaigns to educate stakeholders (customers) about the efficacy and safety of our products to ensure appropriate use.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Post-marketing begins when the medicine or vaccine is released to the market. It includes activities to monitor and evaluate the product for safety and efficacy in a real-world setting.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                                    <li>\n                                <div>\n                                                                            <small class=\"text-descriptive mco-article-slideshow-caption\">Companies monitor approved medicines for as long as they are on the market. This meets regulatory reporting requirements, provides internal reporting for ongoing analyses and supplies data to support the safety of the product.<\/small>\n                                                                                                        <\/div>\n                            <\/li>\n                                            <\/ul>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/section>\n\n\n\n<p class=\"has-text-align-center\"><a class=\"btn\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2024\/04\/TheJourneyofaMolecule___INFOGRAPHIC.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Download the infographic<\/a><\/p>\n\n\n<div id=\"mco-b5-content-block-block_8112641ef41ddb31a90b6785147d48ba\"\n     class=\"mco-b5-content-block mccberg-block negative left\">\n    <div class=\"wrapper\">\n\t\t\t\t\t\t\t            <div class=\"mco-b5-content-block-image-section \">\n\t\t\t\t                <picture aria-label=\"Scientist smiling wearing goggles\">\n                                                                        <source media=\"(max-width: 767px)\"\n                                    data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=696,425\" \/>\n                                                                                                <source media=\"(min-width: 768px) and (max-width: 1199px)\"\n                                    data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=384,468\" \/>\n                                                                                                <source media=\"(min-width: 1200px)\"\n                                    data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=750,650\" \/>\n                                                                                                <source media=\"(min-width: 1600px)\"\n                                    data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=850,744\" \/>\n                                                                                                <source media=\"(min-width: 1920px)\"\n                                    data-srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=980,832\" \/>\n                                                                                                <img\n                                data-src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/05\/Scientists-RY-3D-Technology-Female-Researcher-0413-1-HI-1-e1687981510508.jpg?resize=650,544\"\n                                alt=\"Scientist smiling wearing goggles\"\n                                class=\"lazyload parallax-scroll\"\n                                loading=\"lazy\"\n                            \/>\n                                                            <\/picture>\n\t\t\t\t            <\/div>\n\t\t        <div class=\"mco-b5-content-block-content-section\">\n\t\t\t\n\t\t\t                <h3 class=\"mco-b5-content-block-heading mcc-b5-normal-title\">\n                    Start your journey with us                <\/h3 >\n\t\t\t\n\t\t\t                <div class=\"mco-b5-content-block-description\"><p>Are you passionate about building a meaningful career? Come work with us!<\/p>\n<\/div>\n\t\t\t\n                        <div class=\"mco-b5-content-block-content-buttons-container\">\n\t\t\t\t                    <a class=\"btn secondary read_more\"\n                       href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/careers\/\"\n                       title=\"Explore jobs\"\n                                              target=\"\">Explore jobs<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<div class=\"mco-b5-content-block-modal popup\" style=\"display: none;\" role=\"dialog\" >\n    <div class=\"popup-wrapper\">\n        <div class=\"mco-b5-content-block-modal-content popup-content\">\n            <button class=\"mco-b5-content-block-modal-close popup-close\" >&times;<\/button>\n            <div class=\"mco-b5-content-block-modal-video\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Download the infographic<\/p>\n","protected":false},"author":248,"featured_media":0,"parent":3623710,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"inpsyde_pem_expiration_date":[],"inpsyde_pem_expiration_action":[],"editor_notices":[],"footnotes":""},"class_list":["post-3634160","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The journey of a molecule - Merck.com<\/title>\n<meta name=\"description\" content=\"The journey of a molecule. 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