{"id":3641471,"date":"2024-05-08T11:13:29","date_gmt":"2024-05-08T15:13:29","guid":{"rendered":"https:\/\/vip2-msd.com\/merckcom-migrated\/?post_type=story&p=3641471"},"modified":"2024-05-08T11:13:30","modified_gmt":"2024-05-08T15:13:30","slug":"vaccine-pioneers","status":"publish","type":"story","link":"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/vaccine-pioneers\/","title":{"rendered":"Vaccine inventors, creators and innovators"},"content":{"rendered":"\n
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\n \n \n \n Innovation <\/small>\n <\/a>\n \n \n

\n Vaccine inventors, creators and innovators\n <\/h1>\n

Dr. Maurice Hilleman was among the pioneering scientists who made strides in vaccine history and the fight against infectious disease<\/p>\n <\/div>\n\n

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May 8, 2024<\/p>\n

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Dr. Maurice Hilleman, who led our department of virus and cell biology from 1957 to 1984.<\/p>\n\n\n\n

When were vaccines invented?<\/h2>\n\n\n\n

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The story of modern day vaccines began in 1796 when Dr. Edward Jenner inoculated 9-year-old James Phipps with cowpox as a way to protect him from smallpox. The term \u2018vaccine\u2019 is later coined, taken from the Latin word for cow, vacca. Smallpox was the first disease people tried to prevent by intentionally inoculating themselves with infected matter.<\/p>\n<\/div>\n\n\n\n

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Dr. Edward Jenner inoculating 9-year-old James Phipps with cowpox.<\/p>\n<\/div>\n<\/div>\n\n\n\n

Eight decades after Jenner published his findings, Louis Pasteur developed the first live attenuated rabies vaccine. Attenuation is a process that weakens the bacteria or virus in a vaccine so it\u2019s less likely to cause disease, while still triggering an immune response similar to the natural infection. During the mid- to late-20th century, advances in basic and clinical research made it possible for scientists to develop vaccines to help protect against both bacterial and viral diseases.<\/p>\n\n\n\n

Dr. Maurice Hilleman\u2019s contribution to vaccine development<\/h2>\n\n\n\n

The names Jonas Salk and Albert Sabin have become synonymous with their inventions and developments around the polio vaccine, and the giant strides they made in the fight against viral diseases. Although these are some of the most famous names in vaccine research, Merck has a legacy of vaccine pioneers, too. Dr. Maurice Hilleman, who led Merck\u2019s department of virus and cell biology from 1957 to 1984, also belonged to that distinguished group. Credited with helping to develop more than 40 experimental and licensed human and animal vaccines, Hilleman\u2019s passionate commitment continues to inspire scientists in medical research laboratories to this day.<\/p>\n\n\n\n

Hilleman was born and raised on a farm in Montana. It was a hard life, but a farm background was a great foundation for his later work.<\/p>\n\n\n\n

\u201cWhen you’re brought up on a farm, you have a lot of general knowledge,\u201d he said. After graduating from the University of Chicago with a doctorate in microbiology and chemistry, Hilleman chose to work at a pharmaceutical company instead of academia.<\/p>\n\n\n\n

Despite his many accomplishments, including helping to develop more than 40 human and animal vaccines, Hilleman\u2019s name is virtually unknown by the general public and press. Yet his impact on public health is undeniable.<\/p>\n\n\n\n

“His commitment was to make something useful and convert it to clinical use. Maurice’s genius was in developing vaccines, reliably reproducing them, and he was in charge of all pharmaceutical facets from research to the marketplace.”<\/h3>\n\n\n\n