{"id":3663075,"date":"2023-04-05T10:05:00","date_gmt":"2023-04-05T14:05:00","guid":{"rendered":"https:\/\/vip2-msd.com\/merckcom-migrated\/?post_type=story&#038;p=3663075"},"modified":"2025-10-30T08:44:57","modified_gmt":"2025-10-30T12:44:57","slug":"heart-failure-a-physicians-perspective","status":"publish","type":"story","link":"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/heart-failure-a-physicians-perspective\/","title":{"rendered":"Heart failure: A physician\u2019s perspective"},"content":{"rendered":"\n<div id=\"mco-f1-article-hero-block_eb675db0477cf1eca557bc56cbdf20cc\" class=\"mco-f1-article-hero mccberg-block\">\n    <div class=\"mco-f1-article-hero-content-container\">\n        \n                            <a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/content_topic\/health-awareness\/\">\n                    <small class=\"tagline\">Health awareness<\/small>\n                <\/a>\n            \n        \n                    <h1>\n                Heart failure: A physician\u2019s perspective\n            <\/h1>\n                            <p>By Dr. Joerg Koglin, senior vice president and head of general medicine and global clinical development<\/p>\n            <\/div>\n\n    <div class=\"mco-f1-article-hero-date-container\">\n                    <p class=\"mco-f1-article-hero-date text-descriptive\">April 5, 2023<\/p>\n                <div class=\"mco-f1-article-share-btn-container\">\n                            <p class=\"text-descriptive\">Share this article<\/p>\n                                        <p><a href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/heart-failure-a-physicians-perspective\/\" target=\"_blank\" aria-label=\"Share on Facebook\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"nonzero\" d=\"M6.023 16L6 9H3V6h3V4c0-2.7 1.672-4 4.08-4 1.153 0 2.144.086 2.433.124v2.821h-1.67c-1.31 0-1.563.623-1.563 1.536V6H13l-1 3H9.28v7H6.023z\" \/>\n<title>Facebook icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"https:\/\/twitter.com\/intent\/tweet?text=https%3A%2F%2Fvip2-msd.com%2Fmerckcom-migrated%2Fstories%2Fheart-failure-a-physicians-perspective%2F Heart failure: A physician\u2019s perspective\" target=\"_blank\" aria-label=\"Share on X\">\n<!-- Generator: Adobe Illustrator 27.7.0, SVG Export Plug-In . SVG Version: 6.00 Build 0)  -->\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" width=\"16\" height=\"16\">\n\n\t.st0{fill:#00857C;}\n\n<path class=\"st0\" fill=\"#00857C\" d=\"M9.5,6.8l5.7-6.6h-1.4L8.8,6l-4-5.8H0.3l6,8.7l-6,7h1.4l5.2-6.1l4.2,6.1h4.6L9.5,6.8L9.5,6.8z M7.6,9L7,8.1\n\tL2.2,1.2h2.1l3.9,5.6l0.6,0.9l5.1,7.3h-2.1L7.6,9L7.6,9z\" \/>\n<title>X icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"https:\/\/www.linkedin.com\/sharing\/share-offsite\/?url=https%3A%2F%2Fvip2-msd.com%2Fmerckcom-migrated%2Fstories%2Fheart-failure-a-physicians-perspective%2F\" target=\"_blank\" aria-label=\"Share on LinkedIn\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"evenodd\" d=\"M15.205 0H.695C.299 0 0 .3 0 .7v14.7c0 .3.298.6.696.6h14.608c.398 0 .696-.3.696-.7V.7c-.1-.4-.398-.7-.795-.7zM4.671 13.6H2.385V6H4.77v7.6h-.1zM3.578 5c-.795 0-1.392-.7-1.392-1.4 0-.8.597-1.4 1.392-1.4.795 0 1.39.6 1.39 1.4-.098.7-.695 1.4-1.39 1.4zm9.938 8.6H11.13V9.9c0-.9 0-2-1.192-2-1.193 0-1.391 1-1.391 2v3.8H6.16V6h2.286v1c.298-.6 1.093-1.2 2.187-1.2 2.385 0 2.782 1.6 2.782 3.6v4.2h.1z\" \/>\n<title>Linkedin icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"mailto:?subject=Heart failure: A physician\u2019s perspective&#038;body=https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/heart-failure-a-physicians-perspective\/ By Dr. Joerg Koglin, senior vice president and head of general medicine and global clinical development\" target=\"_blank\" aria-label=\"Share via email\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"nonzero\" d=\"M16 5.7V14c0 .6-.4 1-1 1H1c-.6 0-1-.4-1-1V5.7l7.5 4.2c.28.14.72.14 1 0L16 5.7zM15 1c.6 0 1 .4 1 1v1.5L8 7.9 0 3.4V2c0-.6.4-1 1-1z\" \/>\n<title>Email icon<\/title><\/svg>\n<\/a><\/p>\n                    <\/div>\n    <\/div>\n\n    <div class=\"mco-f1-article-hero-image-container\">\n        <div class=\"mco-f1-article-image-parent \">\n                            <figure class=\"mccberg-figure\">\n                    <picture>\n                        <source\n                            media=\"(max-width: 767px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=321 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=642 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=963 3x\">\n                        <source\n                            media=\"(min-width: 768px) and (max-width: 1199px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=656 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=1312 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=1968 3x\">\n                        <source\n                            media=\"(min-width: 1200px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=1188 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=2376 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=3564 3x\">\n                        <img decoding=\"async\"\n                            src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=1188\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=1188 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=2376 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2020\/06\/Joerg-Koglin-hero-image.jpg?w=3564 3x\"\n                            alt=\"Joerg Koglin Hero\"\n                            loading=\"eager\" fetchpriority=\"high\"\n                        \/>\n                    <\/picture>\n\n                                    <\/figure>\n            \n                    <\/div>\n    <\/div>\n\n            <div class=\"mco-f1-article-hero-modal popup\" style=\"display: none;\">\n            <div class=\"popup-wrapper\">\n                <div class=\"mco-f1-article-hero-modal-content popup-content\">\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n\n\n\n<p>According to the American Heart Association, 127.9 million adults in the U.S. &#8212; nearly half of all U.S. adults &#8212; have some type of cardiovascular disease. And the implications can be very serious.&nbsp;In fact, cardiovascular disease is the leading cause of death in the U.S., claiming approximately 940,000 lives each year (based on 2022 estimates).&nbsp;There are many types of cardiovascular diseases, one of which is heart failure. Heart failure is when the heart cannot pump properly so that it doesn\u2019t fully support the body\u2019s need for oxygen and blood. And that is where my specialty and passion lie. As a cardiologist, I learned and study how cardiovascular diseases develop to try to find ways to help manage conditions that impact so many people around the world.<\/p>\n\n\n\n<p>For years, I worked in one of the largest European academic centers focused on heart failure and cared for patients with this chronic, progressive condition. I saw how this disease affected my patients\u2019 lives and what it meant to live with its symptoms: swollen feet, legs and ankles; shortness of breath; persistent coughing; and fatigue.<\/p>\n\n\n\n<p>After many years as a physician treating individual patients in a heart failure clinic, I joined the Merck research team to try and impact patient care at a larger scale, but I still carry my patients&#8217; stories with me. I remember the father trying to keep up with his kids, losing his breath just climbing the bleachers at a game. The husband who was waiting on the heart transplant list, but ran out of time. My patients&#8217; struggles with heart failure and the impact it had on their families is what drives my desire to make a difference. They are a big part of why I\u2019m at Merck today, working with a team of world-class scientists to try to advance heart failure research.<\/p>\n\n\n\n<p>Our focus is on trying to help people with heart failure, which impacts more than six million Americans &#8212; a number that is expected to grow to over eight million by 2030. We\u2019re working with a sense of urgency because the prognosis for people with heart failure is poor.<\/p>\n\n\n\n<p>While heart failure is a challenging disease, I\u2019m hopeful about the future of research. More than 60 years ago, my colleagues at Merck delivered their first advance in cardiovascular disease and, today, we\u2019ll keep pushing heart failure research forward.<\/p>\n\n\n\n<p>While science pushes forward, it\u2019s important for all of us to take steps today to protect our hearts by living as healthy a lifestyle as possible. The advice I try to follow myself is all about creating healthy habits: eating healthy food, which means more fresh fruits and vegetables and fewer processed foods; maintaining a healthy weight; getting regular exercise and not smoking. With the busy and hectic lifestyles many of us lead, it can be hard to fit it all in every day, but every little bit counts. I\u2019ve found that in life as in science, small steps, coupled with persistence and dedication, can help make a difference.<\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div id=\"mco-f3-more-stories-block-block_5c3d915cad5b2ba2ac70e995577d6548\" class=\"mco-f3-more-stories-block negative mccberg-block\">\n    <div class=\"mco-f3-stories-container\">\n        <small class=\"tagline\">Discover more stories<\/small>                    <div class=\"mco-f3-stories-slider-container\">\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/5-historical-designations-highlight-groundbreaking-scientific-achievements\/\">5 historical designations highlight groundbreaking scientific achievements<\/a><\/p>\n                    <\/div>\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/this-red-chair-is-a-reminder-that-patients-cant-wait\/\">This red chair is a reminder that patients can&#8217;t wait<\/a><\/p>\n                    <\/div>\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/were-helping-build-a-brighter-future-for-maternal-health-in-america\/\">We&#8217;re helping build a brighter future for maternal health in America<\/a><\/p>\n                    <\/div>\n                                            <\/div>\n            <div class=\"mco-f3-stories-slider-controls-container slider-nav\">\n                                    <div class='slider-nav-item active'><\/div>\n                                    <div class='slider-nav-item '><\/div>\n                                    <div class='slider-nav-item '><\/div>\n                            <\/div>\n            <\/div>\n            <div class=\"mco-f3-content-container\">\n            <a class=\"btn secondary\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/\">View all stories<\/a>\n        <\/div>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>According to the American Heart Association, 127.9 million adults in the U.S. &#8212; nearly half of all U.S. adults &#8212; have some type of cardiovascular disease. And the implications can be very serious.&nbsp;In fact, cardiovascular disease is the leading cause of death in the U.S., claiming approximately 940,000 lives each year (based on 2022 estimates).&nbsp;There [&hellip;]<\/p>\n","protected":false},"featured_media":694820,"template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"inpsyde_pem_expiration_date":[],"inpsyde_pem_expiration_action":[],"footnotes":""},"tags":[201,173],"content_topic":[4],"admin_field":[],"class_list":["post-3663075","story","type-story","status-publish","has-post-thumbnail","hentry","tag-cardio-metabolic-diseases","tag-patients-and-caregivers","content_topic-health-awareness"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Heart failure: A physician\u2019s perspective - Merck.com<\/title>\n<meta name=\"description\" content=\"Dr. Joerg Koglin, senior vice president and head of general medicine and global clinical development\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/heart-failure-a-physicians-perspective\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Heart failure: A physician\u2019s perspective - 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Our focus on cardiovascular diseases includes heart failure and atherosclerotic cardiovascular disease.\\r\\n\\r\\n\\u0026nbsp;\",\"_description\":\"mco_title_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_title_block_content_label\",\"cta_one\":\"\",\"_cta_one\":\"mco_title_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_title_block_cta_two\",\"image\":\"\",\"_image\":\"mco_title_block_image\"},\"align\":\"center\",\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/-->\n\n<!-- wp:acf\/title-block {\"name\":\"acf\/title-block\",\"data\":{\"title\":\"The impact of cardiovascular disease\",\"_title\":\"mco_title_block_title\",\"description\":\"\",\"_description\":\"mco_title_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_title_block_content_label\",\"cta_one\":\"\",\"_cta_one\":\"mco_title_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_title_block_cta_two\",\"image\":\"\",\"_image\":\"mco_title_block_image\"},\"align\":\"center\",\"mode\":\"edit\",\"className\":\"pull-up-stats negative mb-2\"} \/-->\n\n<!-- wp:group {\"className\":\"stat-group mb-2 mb-2\"} -->\n<div class=\"wp-block-group stat-group mb-2\"><!-- wp:acf\/statistics-block {\"name\":\"acf\/statistics-block\",\"data\":{\"stat_statistic\":\"~20.5M\",\"_stat_statistic\":\"stat_block_statistic\",\"stat_caption\":\"Cardiovascular disease\",\"_stat_caption\":\"stat_block_caption\",\"stat_description\":\"Annual deaths worldwide from cardiovascular disease in 2021; \\r\\n~900K annual deaths in the U.S. in 2023\",\"_stat_description\":\"stat_block_description\",\"stat_cta\":\"\",\"_stat_cta\":\"stat_block_cta_link\"},\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/-->\n\n<!-- wp:acf\/statistics-block {\"name\":\"acf\/statistics-block\",\"data\":{\"stat_statistic\":\"~24.1%\",\"_stat_statistic\":\"stat_block_statistic\",\"stat_caption\":\"Hypercholesterolemia\",\"_stat_caption\":\"stat_block_caption\",\"stat_description\":\"Percentage of adults worldwide living with hypercholesterolemia (also known as high cholesterol); ~86M adults in the U.S. are affected\",\"_stat_description\":\"stat_block_description\",\"stat_cta\":\"\",\"_stat_cta\":\"stat_block_cta_link\"},\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/--><\/div>\n<!-- \/wp:group -->\n\n<!-- wp:spacer {\"height\":\"18px\"} -->\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:columns {\"className\":\"mco-columns-wrapping border-top-1\"} -->\n<div class=\"wp-block-columns mco-columns-wrapping border-top-1\"><!-- wp:column {\"width\":\"32%\"} -->\n<div class=\"wp-block-column\" style=\"flex-basis:32%\"><!-- wp:heading {\"level\":3,\"className\":\"mr-2 mt-2\"} -->\n<h3 class=\"wp-block-heading mr-2 mt-2\">Cardiovascular disease<\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:heading {\"level\":3,\"className\":\"mr-2\"} -->\n<h3 class=\"wp-block-heading mr-2\"><\/h3>\n<!-- \/wp:heading --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:paragraph {\"className\":\"mt-2\"} -->\n<p class=\"mt-2\">We continue to build on our history of innovative therapies in heart disease to help increase our understanding and help patients around the world.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:columns {\"className\":\"mco-columns-wrapping border-top-1\"} -->\n<div class=\"wp-block-columns mco-columns-wrapping border-top-1\"><!-- wp:column {\"width\":\"32%\"} -->\n<div class=\"wp-block-column\" style=\"flex-basis:32%\"><!-- wp:heading {\"level\":3,\"className\":\"mr-2 mt-2\"} -->\n<h3 class=\"wp-block-heading mr-2 mt-2\">Hypercholesterolemia<\/h3>\n<!-- \/wp:heading -->\n\n<!-- wp:heading {\"level\":3,\"className\":\"mr-2\"} -->\n<h3 class=\"wp-block-heading mr-2\"><\/h3>\n<!-- \/wp:heading --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:paragraph {\"className\":\"mt-2\"} -->\n<p class=\"mt-2\">Hypercholesterolemia, a type of hyperlipidemia, is a disorder in which there are elevated LDL cholesterol (LDL-C) levels in the blood. About 24% of adults worldwide have hypercholesterolemia, also known as high cholesterol, which is a major causal risk factor for atherosclerotic cardiovascular disease (ASCVD), a leading cause of death. People who have elevated LDL cholesterol levels often have no symptoms, so they may not know they have high LDL cholesterol.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:spacer {\"height\":\"27px\"} -->\n<div style=\"height:27px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/content-teaser-cards {\"name\":\"acf\/content-teaser-cards\",\"data\":{\"title\":\"Read the stories  \",\"_title\":\"mco_content_teaser_cards_title\",\"description\":\"\",\"_description\":\"mco_content_teaser_cards_description\",\"cta_one\":\"\",\"_cta_one\":\"mco_content_teaser_cards_block_cta_one\",\"cta_one_aria_label\":\"\",\"_cta_one_aria_label\":\"mco_content_teaser_cards_block_cta_one_aria_label\",\"card_count\":\"4\",\"_card_count\":\"mco_content_teaser_cards_count\",\"show_tags\":\"1\",\"_show_tags\":\"mco_content_teaser_cards_block_show_tags\",\"use_automatic_height\":\"0\",\"_use_automatic_height\":\"mco_content_teaser_cards_block_use_automatic_height\",\"content_selection\":\"manual\",\"_content_selection\":\"mco_content_teaser_cards_content_selection\",\"story_one\":3672534,\"_story_one\":\"mco_content_teaser_cards_block_story_one\",\"story_two\":3663075,\"_story_two\":\"mco_content_teaser_cards_block_story_two\",\"story_three\":3675360,\"_story_three\":\"mco_content_teaser_cards_block_story_three\",\"story_four\":3675150,\"_story_four\":\"mco_content_teaser_cards_block_story_four\"},\"mode\":\"edit\"} \/-->\n\n<!-- wp:acf\/featured-banner-block {\"name\":\"acf\/featured-banner-block\",\"data\":{\"mco_featured_banner_negative\":\"1\",\"_mco_featured_banner_negative\":\"mco_featured_banner_negative_294ytohe\",\"image\":2794923,\"_image\":\"mco_featured_banner_block_image\",\"image_alt_text\":\"\",\"_image_alt_text\":\"mco_featured_banner_block_image_alt_text\",\"title\":\"Careers\",\"_title\":\"mco_featured_banner_block_title\",\"description\":\"To make an impact in cardiovascular disease, we rely on world-class expertise. 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