{"id":3663350,"date":"2025-03-26T16:18:09","date_gmt":"2025-03-26T20:18:09","guid":{"rendered":"https:\/\/vip2-msd.com\/merckcom-migrated\/?post_type=story&#038;p=3663350"},"modified":"2025-03-27T13:34:59","modified_gmt":"2025-03-27T17:34:59","slug":"understanding-melanoma-the-signs-and-risk-factors","status":"publish","type":"story","link":"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/understanding-melanoma-the-signs-and-risk-factors\/","title":{"rendered":"Understanding melanoma: The signs and risk factors"},"content":{"rendered":"\n<div id=\"mco-f1-article-hero-block_abe90f751a4ae20203e561d224df0973\" class=\"mco-f1-article-hero mccberg-block\">\n    <div class=\"mco-f1-article-hero-content-container\">\n        \n                            <a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/content_topic\/health-awareness\/\">\n                    <small class=\"tagline\">Health awareness<\/small>\n                <\/a>\n            \n        \n                    <h1>\n                Understanding melanoma: The signs and risk factors\n            <\/h1>\n                            <p>Learn more about how to monitor your skin for melanoma and ways to help prevent it<\/p>\n            <\/div>\n\n    <div class=\"mco-f1-article-hero-date-container\">\n                    <p class=\"mco-f1-article-hero-date text-descriptive\">March 26, 2025<\/p>\n                <div class=\"mco-f1-article-share-btn-container\">\n                            <p class=\"text-descriptive\">Share this article<\/p>\n                                        <p><a href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/understanding-melanoma-the-signs-and-risk-factors\/\" target=\"_blank\" aria-label=\"Share on Facebook\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"nonzero\" d=\"M6.023 16L6 9H3V6h3V4c0-2.7 1.672-4 4.08-4 1.153 0 2.144.086 2.433.124v2.821h-1.67c-1.31 0-1.563.623-1.563 1.536V6H13l-1 3H9.28v7H6.023z\" \/>\n<title>Facebook icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"https:\/\/twitter.com\/intent\/tweet?text=https%3A%2F%2Fvip2-msd.com%2Fmerckcom-migrated%2Fstories%2Funderstanding-melanoma-the-signs-and-risk-factors%2F Understanding melanoma: The signs and risk factors\" target=\"_blank\" aria-label=\"Share on X\">\n<!-- Generator: Adobe Illustrator 27.7.0, SVG Export Plug-In . SVG Version: 6.00 Build 0)  -->\n<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 16 16\" width=\"16\" height=\"16\">\n\n\t.st0{fill:#00857C;}\n\n<path class=\"st0\" fill=\"#00857C\" d=\"M9.5,6.8l5.7-6.6h-1.4L8.8,6l-4-5.8H0.3l6,8.7l-6,7h1.4l5.2-6.1l4.2,6.1h4.6L9.5,6.8L9.5,6.8z M7.6,9L7,8.1\n\tL2.2,1.2h2.1l3.9,5.6l0.6,0.9l5.1,7.3h-2.1L7.6,9L7.6,9z\" \/>\n<title>X icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"https:\/\/www.linkedin.com\/sharing\/share-offsite\/?url=https%3A%2F%2Fvip2-msd.com%2Fmerckcom-migrated%2Fstories%2Funderstanding-melanoma-the-signs-and-risk-factors%2F\" target=\"_blank\" aria-label=\"Share on LinkedIn\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"evenodd\" d=\"M15.205 0H.695C.299 0 0 .3 0 .7v14.7c0 .3.298.6.696.6h14.608c.398 0 .696-.3.696-.7V.7c-.1-.4-.398-.7-.795-.7zM4.671 13.6H2.385V6H4.77v7.6h-.1zM3.578 5c-.795 0-1.392-.7-1.392-1.4 0-.8.597-1.4 1.392-1.4.795 0 1.39.6 1.39 1.4-.098.7-.695 1.4-1.39 1.4zm9.938 8.6H11.13V9.9c0-.9 0-2-1.192-2-1.193 0-1.391 1-1.391 2v3.8H6.16V6h2.286v1c.298-.6 1.093-1.2 2.187-1.2 2.385 0 2.782 1.6 2.782 3.6v4.2h.1z\" \/>\n<title>Linkedin icon<\/title><\/svg>\n<\/a><\/p>\n                <p><a href=\"mailto:?subject=Understanding melanoma: The signs and risk factors&#038;body=https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/understanding-melanoma-the-signs-and-risk-factors\/ Learn more about how to monitor your skin for melanoma and ways to help prevent it\" target=\"_blank\" aria-label=\"Share via email\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\">\n    <path fill=\"#00857C\" fill-rule=\"nonzero\" d=\"M16 5.7V14c0 .6-.4 1-1 1H1c-.6 0-1-.4-1-1V5.7l7.5 4.2c.28.14.72.14 1 0L16 5.7zM15 1c.6 0 1 .4 1 1v1.5L8 7.9 0 3.4V2c0-.6.4-1 1-1z\" \/>\n<title>Email icon<\/title><\/svg>\n<\/a><\/p>\n                    <\/div>\n    <\/div>\n\n    <div class=\"mco-f1-article-hero-image-container\">\n        <div class=\"mco-f1-article-image-parent \">\n                            <figure class=\"mccberg-figure\">\n                    <picture>\n                        <source\n                            media=\"(max-width: 767px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=321 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=642 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=963 3x\">\n                        <source\n                            media=\"(min-width: 768px) and (max-width: 1199px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=656 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=1312 2x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=1968 3x\">\n                        <source\n                            media=\"(min-width: 1200px)\"\n                            srcset=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=1188 1x,\n                    https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/03\/understanding-melanoma-signs-and-risk-factors-hero.jpg?w=2376 2x,\n                    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                   loading=\"eager\" fetchpriority=\"high\"\n                        \/>\n                    <\/picture>\n\n                                    <\/figure>\n            \n                    <\/div>\n    <\/div>\n\n            <div class=\"mco-f1-article-hero-modal popup\" style=\"display: none;\">\n            <div class=\"popup-wrapper\">\n                <div class=\"mco-f1-article-hero-modal-content popup-content\">\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n\n\n\n<h2 class=\"wp-block-heading\">What is melanoma?<\/h2>\n\n\n\n<p>Melanoma is a form of skin cancer. Characterized by the uncontrolled growth of pigment-producing cells, melanoma accounted for approximately 1.7% of new cancer cases worldwide in 2022.<\/p>\n\n\n\n<p class=\"mb-2\">Exposure to ultraviolent (UV) radiation, either from the sun or other sources such as tanning beds and sunlamps, is a major risk factor for skin cancers, including melanoma. While melanoma can occur anywhere on the skin, including areas without sun exposure, it\u2019s more likely to start in certain locations, like the face and neck, legs (most common in women), and chest and back (most common in men).<\/p>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping mb-2 mt-2 is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image mt-2 mb-2\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"4517\" height=\"2485\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-09.jpg?w=1024\" alt=\"Illustration of a man and woman and the most common locations of melanoma\" class=\"wp-image-3663561\" title=\"mt-2\"\/><\/figure><\/div>\n\n\n<p>The risk of melanoma generally increases with age and incidence is greater among older populations. However, even among patients younger than 30 years, melanoma is one of the most common cancers, especially in young women.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Worldwide, the melanoma diagnosis rate has risen over the past two decades<\/h2>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image mt-2 mb-2\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2051\" height=\"1769\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_Stat-Callout.jpg\" alt=\"\" class=\"wp-image-3663569\"\/><\/figure><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center\">331,000+<\/h1>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center mb-2\">Estimated number of new melanoma cases worldwide in 2022<\/h4>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Signs of cancerous moles<\/h2>\n\n\n\n<p>A new spot on the skin or a spot that is changing in size, shape or color, or one that looks different, is an important warning sign of melanoma and should be checked by a doctor. The ABCDE rule can be used as a guide to help identify the warning signs of melanoma:<\/p>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"498\" height=\"509\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/03\/abcdes-of-melanoma-picture-A.jpg\" alt=\"Illustration of Asymmetry\" class=\"wp-image-3610609\"\/><\/figure><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>A is for Asymmetry<\/strong><\/p>\n\n\n\n<p>One half of a mole or spot does not match the other.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"498\" height=\"509\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/03\/abcdes-of-melanoma-picture-B.jpg\" alt=\"Illustration of border\" class=\"wp-image-3610611\"\/><\/figure><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>B is for Border<\/strong><\/p>\n\n\n\n<p>The edges of the spot are irregular, scalloped or poorly defined.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"498\" height=\"509\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/03\/abcdes-of-melanoma-picture-C.jpg\" alt=\"Illustration of color\" class=\"wp-image-3610612\"\/><\/figure><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>C is for Color<\/strong><\/p>\n\n\n\n<p>The color of the spot is not the same all over and may include different shades of brown or black, sometimes with patches of pink, red, white or blue.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"498\" height=\"509\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/03\/abcdes-of-melanoma-picture-D.jpg\" alt=\"Illustration of diameter\" class=\"wp-image-3610613\"\/><\/figure><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>D is for Diameter<\/strong><\/p>\n\n\n\n<p>The spot is larger than 6 millimeters across. Melanoma is usually larger than 6 millimeters in size (about 1\/4-inch or the size of a pencil eraser) when diagnosed. However, it can sometimes be smaller.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>E is for Evolving<\/strong><\/p>\n\n\n\n<p>The mole is changing in size, shape, or color.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"2248\" height=\"509\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2021\/04\/melanoma-E.jpg?w=1024\" alt=\"Illustration of evolving\" class=\"wp-image-2778596\"\/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<p>Any of these warning signs should be discussed with a doctor, especially if you feel you are at risk for melanoma.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Causes of melanoma<\/h2>\n\n\n\n<p>There are many risk factors and causes of melanoma, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>UV light on your skin, such as from the sun or a tanning bed (the most common risk factor for most cases of melanoma)<\/li>\n\n\n\n<li>Age &#8212; melanoma is more common in older people, but younger people are also at risk. Melanoma is one of the most common cancers in people younger than 30 years (especially among women)<\/li>\n\n\n\n<li>Moles \u2014 having many moles, irregular or large moles, or atypical moles<\/li>\n\n\n\n<li>Personal or family history \u2013 Melanoma can be genetic and having a relative with melanoma can increase your risk <\/li>\n\n\n\n<li>Fair skin or a fair complexion, a lot of freckles and\/or light-colored hair and eyes<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ways to lower your risk of melanoma<\/h2>\n\n\n\n<p>Melanoma can\u2019t be entirely prevented, but there are ways to lower your risk. The number one way to lower risk is to protect against UV rays, which damage the DNA of skin cells and impact the genes that control skin cell growth. That\u2019s why it\u2019s important to avoid tanning beds, booths, sunlamps and other artificial sources of UV radiation. However, the top source of UV rays is the sun. That\u2019s why it\u2019s important to practice sun safety every time you go outside, even on cloudy days when UV rays can still shine through. Here are a few ways to protect yourself:<\/p>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1364\" height=\"963\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-01.jpg?w=1024\" alt=\"illustration of beach chair and umbrella on sand\" class=\"wp-image-3663555\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading has-text-align-left\">Seek shade<\/h5>\n\n\n\n<p class=\"has-text-align-left\">UV exposure is greatest between the hours of 10 a.m. and 4 p.m. If you need to be outside during these hours, seek shade \u2013 under a tree, an umbrella or an awning.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1364\" height=\"963\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-02.jpg?w=1024\" alt=\"illustration of person wearing big beach hat\" class=\"wp-image-3663556\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading has-text-align-left\">Wear a hat<\/h5>\n\n\n\n<p class=\"has-text-align-left\">Try to find a hat with a wide brim \u2013 at least 2 or 3 inches wide \u2013 to protect your face, top of the head, ears and neck.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1364\" height=\"963\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-04.jpg?w=1024\" alt=\"illustration of person holding long sleeve shirt\" class=\"wp-image-3663557\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading has-text-align-left\">Cover up<\/h5>\n\n\n\n<p class=\"has-text-align-left\">Choose clothing with a tight knit or weave, and avoid shirts that you can see through. Remember, if light is getting through, then UV rays are too.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns mco-columns-wrapping is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1364\" height=\"963\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-05.jpg?w=1024\" alt=\"illustration of adult applying sunscreen to a child\" class=\"wp-image-3663558\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading has-text-align-left\">Use sunscreen<\/h5>\n\n\n\n<p class=\"has-text-align-left\">For extended outdoor activity, use a water-resistant, broad spectrum sunscreen with an SPF of 30 or higher.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1364\" height=\"963\" src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2025\/02\/Melanoma_Illustrations_v2-06.jpg?w=1024\" alt=\"illustration of hand holding sunglasses\" class=\"wp-image-3663559\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading has-text-align-left\">Wear sunglasses<\/h5>\n\n\n\n<p class=\"has-text-align-left\">Protect your eyes and the sensitive skin around them. Pick a pair of sunglasses that will block as close to 100 percent of both UVA and UVB rays as possible.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div style=\"height:103px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div id=\"mco-f3-more-stories-block-block_e9707f0e3b3e15fbf7be3ea95a4c4ffb\" class=\"mco-f3-more-stories-block negative mccberg-block\">\n    <div class=\"mco-f3-stories-container\">\n        <small class=\"tagline\">Discover more stories<\/small>                    <div class=\"mco-f3-stories-slider-container\">\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/5-historical-designations-highlight-groundbreaking-scientific-achievements\/\">5 historical designations highlight groundbreaking scientific achievements<\/a><\/p>\n                    <\/div>\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/this-red-chair-is-a-reminder-that-patients-cant-wait\/\">This red chair is a reminder that patients can&#8217;t wait<\/a><\/p>\n                    <\/div>\n                                                        <div class=\"mco-f3-story\">\n                        <p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/were-helping-build-a-brighter-future-for-maternal-health-in-america\/\">We&#8217;re helping build a brighter future for maternal health in America<\/a><\/p>\n                    <\/div>\n                                            <\/div>\n            <div class=\"mco-f3-stories-slider-controls-container slider-nav\">\n                                    <div class='slider-nav-item active'><\/div>\n                                    <div class='slider-nav-item '><\/div>\n                                    <div class='slider-nav-item '><\/div>\n                            <\/div>\n            <\/div>\n            <div class=\"mco-f3-content-container\">\n            <a class=\"btn secondary\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/\">View all stories<\/a>\n        <\/div>\n    <\/div>","protected":false},"excerpt":{"rendered":"<p>What is melanoma? Melanoma is a form of skin cancer. Characterized by the uncontrolled growth of pigment-producing cells, melanoma accounted for approximately 1.7% of new cancer cases worldwide in 2022. Exposure to ultraviolent (UV) radiation, either from the sun or other sources such as tanning beds and sunlamps, is a major risk factor for skin [&hellip;]<\/p>\n","protected":false},"featured_media":3665655,"template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"inpsyde_pem_expiration_date":[],"inpsyde_pem_expiration_action":[],"footnotes":""},"tags":[137],"content_topic":[4],"admin_field":[],"class_list":["post-3663350","story","type-story","status-publish","has-post-thumbnail","hentry","tag-oncology","content_topic-health-awareness"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Understanding melanoma: The signs and risk factors - Merck.com<\/title>\n<meta name=\"description\" content=\"Read more about melanoma and how to detect and prevent one of the most serious types of skin cancer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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These cancers typically do not cause symptoms until they have reached an advanced stage.\",\"_mco_b6_accordion_list_row_3_mco_b6_accordion_list_row_details\":\"mco_b6_accordion_list_row_details_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_3_mco_b6_accordion_list_row_image\":\"\",\"_mco_b6_accordion_list_row_3_mco_b6_accordion_list_row_image\":\"mco_b6_accordion_list_row_image_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_3_mco_b6_accordion_list_row_open\":\"0\",\"_mco_b6_accordion_list_row_3_mco_b6_accordion_list_row_open\":\"mco_b6_accordion_list_row_open_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_4_mco_b6_accordion_list_row_summary\":\"Gynecological 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is a serious form of skin cancer, and rates of the disease have been continuing to rise over the last several decades.\",\"_mco_b6_accordion_list_row_7_mco_b6_accordion_list_row_details\":\"mco_b6_accordion_list_row_details_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_7_mco_b6_accordion_list_row_image\":\"\",\"_mco_b6_accordion_list_row_7_mco_b6_accordion_list_row_image\":\"mco_b6_accordion_list_row_image_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_7_mco_b6_accordion_list_row_open\":\"0\",\"_mco_b6_accordion_list_row_7_mco_b6_accordion_list_row_open\":\"mco_b6_accordion_list_row_open_6947uhf9ywhuj\",\"mco_b6_accordion_list_row_8_mco_b6_accordion_list_row_summary\":\"Prostate 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Immuno-oncology\",\"_mcc_b7_related_links_0_mcc_b7_related_links_sub_title\":\"mcc_b7_related_links_sub_title_field\",\"mcc_b7_related_links_0_mcc_b7_related_links_description\":\"Boosting anti-tumor responses by combining foundational cancer treatments with negative immune regulators that play different roles in adjusting the immune 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licensing<\/a><\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:paragraph {\"align\":\"center\"} -->\n<p class=\"has-text-align-center\"><a class=\"btn\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/clinical-trials\/\">Find a cancer clinical trial<\/a><\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:html -->\n<p class=\"has-text-align-center\"><a class=\"btn\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/product-pipeline\/\">Explore our pipeline<\/a><\/p>\n<!-- \/wp:html --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:paragraph -->\n<p><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading {\"level\":1} -->\n<h1 class=\"wp-block-heading\"><\/h1>\n<!-- \/wp:heading -->\n\n<!-- wp:html -->\n<a id=\"support\"><\/a>\n<!-- \/wp:html -->\n\n<!-- wp:spacer {\"height\":\"40px\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/title-block {\"name\":\"acf\/title-block\",\"data\":{\"title\":\"Supporting the cancer community\",\"_title\":\"mco_title_block_title\",\"description\":\"We work with the entire oncology community \\u002d\\u002d advocacy partners, health care providers, governments and industry colleagues \\u002d\\u002d to create programs that help patients and caregivers on their journeys, as well as provide grants to organizations that support patients with cancer.\",\"_description\":\"mco_title_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_title_block_content_label\",\"cta_one\":\"\",\"_cta_one\":\"mco_title_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_title_block_cta_two\",\"image\":\"\",\"_image\":\"mco_title_block_image\"},\"align\":\"center\",\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/-->\n\n<!-- wp:acf\/three-column-content-block 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wp:acf\/content-block {\"name\":\"acf\/content-block\",\"data\":{\"maintain_image_aspect_ratio\":\"0\",\"_maintain_image_aspect_ratio\":\"content_block_maintain_image_aspect_ratio\",\"negative_style\":\"1\",\"_negative_style\":\"content_block_negative\",\"content_selection\":\"static\",\"_content_selection\":\"content_selction_method\",\"content_block_image\":3652899,\"_content_block_image\":\"content_block_image\",\"content_block_heading\":\"Drug discovery\",\"_content_block_heading\":\"content_block_heading\",\"content_block_body\":\"Drug discovery and development is a complex and lengthy process. It requires creativity, tenacity and agility and the expertise of thousands of scientists working diligently toward our goal to save and improve lives around the world.\",\"_content_block_body\":\"content_block_body\",\"content_block_cta\":{\"title\":\"How we invent\",\"url\":\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/discovery-development\/\",\"target\":\"\"},\"_content_block_cta\":\"content_block_cta\",\"content_block_aria_label\":\"\",\"_content_block_aria_label\":\"content_block_aria_label\",\"content_block_optional_cta\":\"\",\"_content_block_optional_cta\":\"content_block_optional_cta\",\"content_block_optional_cta_aria_label\":\"\",\"_content_block_optional_cta_aria_label\":\"content_block_optional_cta_aria_label\",\"content_block_optional_tag\":\"\",\"_content_block_optional_tag\":\"content_block_optional_tag\",\"content_block_video\":\"\",\"_content_block_video\":\"content_block_video\",\"content_media_position\":\"right\",\"_content_media_position\":\"content_media_position\",\"brightcove_account_id\":\"\",\"_brightcove_account_id\":\"bright_cove_account_id\",\"content_block_video_accessible_name\":\"\",\"_content_block_video_accessible_name\":\"content_block_video_accessible_name\",\"content_block_play_button_accessible_name\":\"\",\"_content_block_play_button_accessible_name\":\"content_block_play_button_accessible_name\",\"content_block_popup_accessible_name\":\"\",\"_content_block_popup_accessible_name\":\"content_block_popup_accessible_name\",\"content_block_popup_close_button_accessible_name\":\"\",\"_content_block_popup_close_button_accessible_name\":\"content_block_popup_close_button_accessible_name\"},\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/--><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\">Meet our scientists<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Innovation is fueled by diverse expertise and backgrounds. Our R&amp;D leaders are pushing scientific boundaries at Merck. <a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/meet-our-scientists\/\">Meet our scientists<\/a>.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:columns {\"className\":\"mco-columns-wrapping\"} -->\n<div class=\"wp-block-columns mco-columns-wrapping\"><!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:image {\"id\":3627832,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/09\/Dean__Li.jpg?w=666\" alt=\"photo of Dean Li\" class=\"wp-image-3627832\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/meet-our-scientists\/dean-li-md-ph-d\/\"><strong>Dean Li<\/strong><\/a><br>Executive vice president and president, Merck Research Laboratories<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:image {\"id\":3627836,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/09\/EliavBarr.jpg?w=666\" alt=\"\" class=\"wp-image-3627836\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/meet-our-scientists\/eliav-barr-md\/\"><strong>Eliav Barr<\/strong><\/a><br>Senior vice president, head of global clinical development and chief medical officer<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:image {\"id\":3636453,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img src=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2023\/11\/George_AddonaFinal.png?w=666\" alt=\"\" class=\"wp-image-3636453\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/meet-our-scientists\/george-addona-ph-d\/\"><strong>George Addona<\/strong><\/a><br>Senior vice president and head, discovery, preclinical development and translational medicine<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:acf\/content-block {\"name\":\"acf\/content-block\",\"data\":{\"maintain_image_aspect_ratio\":\"0\",\"_maintain_image_aspect_ratio\":\"content_block_maintain_image_aspect_ratio\",\"negative_style\":\"1\",\"_negative_style\":\"content_block_negative\",\"content_selection\":\"static\",\"_content_selection\":\"content_selction_method\",\"content_block_image\":3655596,\"_content_block_image\":\"content_block_image\",\"content_block_heading\":\"Postdoctoral Research Fellows Program\",\"_content_block_heading\":\"content_block_heading\",\"content_block_body\":\"Our Postdoctoral Research Fellows Program aims to be a best-in-industry experience for Ph.D. graduates, providing academic focus in a large pharmaceutical environment.\",\"_content_block_body\":\"content_block_body\",\"content_block_cta\":{\"title\":\"Learn more about our program\",\"url\":\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/postdoctoral-research-fellows-program\/\",\"target\":\"\"},\"_content_block_cta\":\"content_block_cta\",\"content_block_aria_label\":\"\",\"_content_block_aria_label\":\"content_block_aria_label\",\"content_block_optional_cta\":\"\",\"_content_block_optional_cta\":\"content_block_optional_cta\",\"content_block_optional_cta_aria_label\":\"\",\"_content_block_optional_cta_aria_label\":\"content_block_optional_cta_aria_label\",\"content_block_optional_tag\":\"\",\"_content_block_optional_tag\":\"content_block_optional_tag\",\"content_block_video\":\"\",\"_content_block_video\":\"content_block_video\",\"content_media_position\":\"left\",\"_content_media_position\":\"content_media_position\",\"brightcove_account_id\":\"\",\"_brightcove_account_id\":\"bright_cove_account_id\",\"content_block_video_accessible_name\":\"\",\"_content_block_video_accessible_name\":\"content_block_video_accessible_name\",\"content_block_play_button_accessible_name\":\"\",\"_content_block_play_button_accessible_name\":\"content_block_play_button_accessible_name\",\"content_block_popup_accessible_name\":\"\",\"_content_block_popup_accessible_name\":\"content_block_popup_accessible_name\",\"content_block_popup_close_button_accessible_name\":\"\",\"_content_block_popup_close_button_accessible_name\":\"content_block_popup_close_button_accessible_name\"},\"mode\":\"edit\"} \/-->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\">Where we work<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Research based on innovation is at the core of who we are and what we do. It starts with the capabilities and expertise at our facilities, but we're open to collaboration anywhere the science leads us. <a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/rd-locations\/\">View all of our R&amp;D locations. <\/a><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:acf\/four-column-content-block 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mb-2\"} \/-->\n\n<!-- wp:acf\/content-teaser-cards {\"name\":\"acf\/content-teaser-cards\",\"data\":{\"title\":\"Read our R\\u0026D 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wp:acf\/featured-banner-block {\"name\":\"acf\/featured-banner-block\",\"data\":{\"mco_featured_banner_negative\":\"1\",\"_mco_featured_banner_negative\":\"mco_featured_banner_negative_294ytohe\",\"image\":3622455,\"_image\":\"mco_featured_banner_block_image\",\"image_alt_text\":\"\",\"_image_alt_text\":\"mco_featured_banner_block_image_alt_text\",\"title\":\"Careers in R\\u0026D\",\"_title\":\"mco_featured_banner_block_title\",\"description\":\"We're calling all aspiring world-class scientists who want to be a part of cutting-edge work to save and improve lives.\",\"_description\":\"mco_featured_banner_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_featured_banner_block_content_label\",\"cta_one\":{\"title\":\"Explore the possibilities\",\"url\":\"https:\/\/jobs.merck.com\/us\/en\/research-laboratories\",\"target\":\"\"},\"_cta_one\":\"mco_featured_banner_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_featured_banner_block_cta_two\"},\"mode\":\"edit\"} \/-->","post_title":"Research","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"research","to_ping":"","pinged":"","post_modified":"2025-09-29 14:02:26","post_modified_gmt":"2025-09-29 18:02:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/vip2-msd.com\/merckcom-migrated\/?page_id=47","menu_order":3,"post_type":"page","post_mime_type":"","comment_count":"0","filter":"raw"},"story_three_selection":"select","related_content_item_three":{"ID":244313,"post_author":"183","post_date":"2020-04-03 17:51:07","post_date_gmt":"2020-04-03 17:51:07","post_content":"<!-- wp:acf\/hero-block {\"name\":\"acf\/hero-block\",\"data\":{\"mco_hero_block_tagline_text\":\"\",\"_mco_hero_block_tagline_text\":\"mco_hero_block_tagline_text\",\"mco_hero_block_ttle\":\"How we invent\",\"_mco_hero_block_ttle\":\"mco_hero_block_title\",\"mco_hero_block_description\":\"Drug discovery and development is a complex and lengthy 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Our teams of scientists bring together diverse expertise and backgrounds, combined with cutting-edge technologies and tools, to help discover the next scientific breakthrough for patients.\",\"_description\":\"mco_title_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_title_block_content_label\",\"cta_one\":\"\",\"_cta_one\":\"mco_title_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_title_block_cta_two\",\"image\":\"\",\"_image\":\"mco_title_block_image\"},\"align\":\"center\",\"mode\":\"edit\",\"className\":\"mb-2 mt-2\"} \/-->\n\n<!-- wp:columns {\"className\":\"mco-columns-wrapping\"} -->\n<div class=\"wp-block-columns mco-columns-wrapping\"><!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:embed {\"url\":\"https:\/\/www.youtube.com\/watch?v=EnH355osvC0\",\"type\":\"video\",\"providerNameSlug\":\"youtube\",\"responsive\":true,\"className\":\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"} -->\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/www.youtube.com\/watch?v=EnH355osvC0\n<\/div><\/figure>\n<!-- \/wp:embed -->\n\n<!-- wp:paragraph -->\n<p><strong>Drug discovery: From hit to lead<\/strong><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Merck scientists explain how new technologies can accelerate the drug discovery process as we use the power of leading-edge science to save and improve lives. <a href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/stories\/harnessing-innovative-technology-in-drug-discovery\/\">Learn more<\/a>.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:embed {\"url\":\"https:\/\/www.youtube.com\/watch?v=qzkJREcf9SM\",\"type\":\"video\",\"providerNameSlug\":\"youtube\",\"responsive\":true,\"className\":\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"} -->\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/www.youtube.com\/watch?v=qzkJREcf9SM\n<\/div><\/figure>\n<!-- \/wp:embed -->\n\n<!-- wp:paragraph -->\n<p><strong>Analytical R&amp;D: Partners in problem solving<\/strong><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Our talented scientists in our analytical research &amp; development team are integrating state-of-the-art physical, analytical and bioanalytical solutions, and applying innovative technologies, to advance our company\u2019s pipeline.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:embed {\"url\":\"https:\/\/www.youtube.com\/watch?v=JxbadQLWLR0\",\"type\":\"video\",\"providerNameSlug\":\"youtube\",\"responsive\":true,\"className\":\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"} -->\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/www.youtube.com\/watch?v=JxbadQLWLR0\n<\/div><\/figure>\n<!-- \/wp:embed -->\n\n<!-- wp:paragraph -->\n<p><strong>Formulation development: Putting the patient first<\/strong><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Our formulation development team explains how leading with a patient-centric approach helps advance our understanding of formulation design, material science and engineering to improve the patient experience.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column -->\n\n<!-- wp:column -->\n<div class=\"wp-block-column\"><!-- wp:embed {\"url\":\"https:\/\/www.youtube.com\/watch?v=eCItDYm78U4\",\"type\":\"video\",\"providerNameSlug\":\"youtube\",\"responsive\":true,\"className\":\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"} -->\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/www.youtube.com\/watch?v=eCItDYm78U4\n<\/div><\/figure>\n<!-- \/wp:embed -->\n\n<!-- wp:paragraph -->\n<p><strong>Clinical supply and manufacturing: Serving patients worldwide<\/strong><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Our clinical supply and pharmaceutical operations teams explain the importance of staying current with trends and advancing technology for optimal clinical trials and patient outcomes.<\/p>\n<!-- \/wp:paragraph --><\/div>\n<!-- \/wp:column --><\/div>\n<!-- \/wp:columns -->\n\n<!-- wp:acf\/title-block {\"name\":\"acf\/title-block\",\"data\":{\"title\":\"From lab to patient: explore the journey of a molecule\",\"_title\":\"mco_title_block_title\",\"description\":\"Drug discovery and development involves dedication and commitment from a wide range of people \u2014 from scientists, data analysts and clinical trial volunteers to manufacturing, regulatory, development, marketing and commercial teams, among many others.\",\"_description\":\"mco_title_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_title_block_content_label\",\"cta_one\":\"\",\"_cta_one\":\"mco_title_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_title_block_cta_two\",\"image\":\"\",\"_image\":\"mco_title_block_image\"},\"align\":\"center\",\"mode\":\"edit\",\"className\":\"mb-2 mt-2\"} \/-->\n\n<!-- wp:acf\/mco-article-slideshow {\"name\":\"acf\/mco-article-slideshow\",\"data\":{\"mco_article_slideshow_0_mco_article_slideshow_image\":3637071,\"_mco_article_slideshow_0_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_0_mco_article_slideshow_caption\":\"Discovery is the process of exploring new and unique molecules, compounds and biologics that may have the potential to treat or prevent disease. We consider variables such as disease prevalence, unmet medical needs and current treatment options when identifying a preclinical candidate (PCC).\",\"_mco_article_slideshow_0_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_0_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_0_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_1_mco_article_slideshow_image\":3637154,\"_mco_article_slideshow_1_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_1_mco_article_slideshow_caption\":\"  It takes about 10 years for a new product to reach the marketplace after the initial discovery.\",\"_mco_article_slideshow_1_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_1_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_1_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_2_mco_article_slideshow_image\":3637073,\"_mco_article_slideshow_2_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_2_mco_article_slideshow_caption\":\"During this phase, the active pharmaceutical ingredient is produced to create the material that will be supplied for the clinical studies.\",\"_mco_article_slideshow_2_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_2_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_2_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_3_mco_article_slideshow_image\":3637155,\"_mco_article_slideshow_3_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_3_mco_article_slideshow_caption\":\"1 in every 5,000 compounds that enter discovery and progress to preclinical development actually become an approved drug.\",\"_mco_article_slideshow_3_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_3_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_3_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_4_mco_article_slideshow_image\":3637075,\"_mco_article_slideshow_4_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_4_mco_article_slideshow_caption\":\"Clinical studies determine the safety and efficacy of our products by gathering evidence through testing and analysis in trial volunteers \u2014 first in healthy volunteers, then in those with the disease. Once we have sufficient safety and efficacy data, we file an application with the information we know about the product \u2014 including study data, analyses and reports \u2014 with a regulatory agency (such as the U.S. Food and Drug Administration) for approval.\",\"_mco_article_slideshow_4_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_4_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_4_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_5_mco_article_slideshow_image\":3637150,\"_mco_article_slideshow_5_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_5_mco_article_slideshow_caption\":\"Less than 12% of investigational medicines that enter clinical testing make it to approval.\",\"_mco_article_slideshow_5_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_5_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_5_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_6_mco_article_slideshow_image\":3637065,\"_mco_article_slideshow_6_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_6_mco_article_slideshow_caption\":\"Manufacturing is the process of industrial-scale production, packaging and distribution of our medicines and vaccines. The process varies from product to product but is always in full compliance with all regulations and Good Manufacturing Practices (GMPs, also referred to as \\u0022cGMPs\\u0022 or \\u0022current GMPs\\u0022) to ensure a compliant, reliable supply for our patients.\",\"_mco_article_slideshow_6_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_6_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_6_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_7_mco_article_slideshow_image\":3637151,\"_mco_article_slideshow_7_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_7_mco_article_slideshow_caption\":\"GMP regulations outline the minimum quality standards for manufacturing and vary by country. Each country has its own agency to monitor meeting the regulations and requirements.\",\"_mco_article_slideshow_7_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_7_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_7_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_8_mco_article_slideshow_image\":3637067,\"_mco_article_slideshow_8_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_8_mco_article_slideshow_caption\":\"Once a product is approved and manufactured, we promote it \u2014  through education and awareness campaigns \u2014  to customers, including physicians, health care providers, pharmacies, patient populations, wholesalers and governments. With a customer- and data-focused approach, we develop a brand strategy to create a unique impression for each product.\",\"_mco_article_slideshow_8_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_8_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_8_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_9_mco_article_slideshow_image\":3637152,\"_mco_article_slideshow_9_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_9_mco_article_slideshow_caption\":\"Marketing teams are key to creating the campaigns to educate stakeholders (customers) about the efficacy and safety of our products to ensure appropriate use.\",\"_mco_article_slideshow_9_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_9_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_9_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_10_mco_article_slideshow_image\":3637069,\"_mco_article_slideshow_10_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_10_mco_article_slideshow_caption\":\"Post-marketing begins when the medicine or vaccine is released to the market. It includes activities to monitor and evaluate the product for safety and efficacy in a real-world setting.\",\"_mco_article_slideshow_10_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_10_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_10_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow_11_mco_article_slideshow_image\":3637153,\"_mco_article_slideshow_11_mco_article_slideshow_image\":\"mco_article_slideshow_image_f9q8hyhfliu\",\"mco_article_slideshow_11_mco_article_slideshow_caption\":\"Companies monitor approved medicines for as long as they are on the market. This meets regulatory reporting requirements, provides internal reporting for ongoing analyses and supplies data to support the safety of the product.\",\"_mco_article_slideshow_11_mco_article_slideshow_caption\":\"mco_article_slideshow_caption_f9q8hyhfliu\",\"mco_article_slideshow_11_mco_article_slideshow_credit\":\"\",\"_mco_article_slideshow_11_mco_article_slideshow_credit\":\"mco_article_slideshow_credit_f9q8hyhfliu\",\"mco_article_slideshow\":12,\"_mco_article_slideshow\":\"mco_article_slideshow_f9q8hyhfliu\"},\"mode\":\"auto\",\"className\":\"mt-2 mb-2\"} \/-->\n\n<!-- wp:paragraph {\"align\":\"center\"} -->\n<p class=\"has-text-align-center\"><a class=\"btn\" href=\"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-content\/uploads\/sites\/152\/2024\/04\/TheJourneyofaMolecule___INFOGRAPHIC.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Download the infographic<\/a><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"5px\"} -->\n<div style=\"height:5px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/content-block {\"name\":\"acf\/content-block\",\"data\":{\"negative_style\":\"0\",\"_negative_style\":\"content_block_negative\",\"content_selection\":\"static\",\"_content_selection\":\"content_selction_method\",\"content_block_image\":3624031,\"_content_block_image\":\"content_block_image\",\"content_block_heading\":\"Clinical trials\",\"_content_block_heading\":\"content_block_heading\",\"content_block_body\":\"Clinical trials are a key part of the drug development process, testing the safety and effectiveness of medicines and vaccines in development and exploring how different people\u2019s bodies respond to them. Ensuring our data represents varied backgrounds advances science and improves lives by reflecting the true \\u003ca href=\\u0022https:\/\/vip2-msd.com\/merckcom-migrated\/research\/diversity-in-clinical-trials\/\\u0022\\u003ediversity\\u003c\/a\\u003e of the populations we aim to serve.\",\"_content_block_body\":\"content_block_body\",\"content_block_cta\":{\"title\":\"Learn more about clinical trials\",\"url\":\"https:\/\/vip2-msd.com\/merckcom-migrated\/research\/clinical-trials\/\",\"target\":\"\"},\"_content_block_cta\":\"content_block_cta\",\"content_block_optional_cta\":\"\",\"_content_block_optional_cta\":\"content_block_optional_cta\",\"content_block_optional_tag\":\"\",\"_content_block_optional_tag\":\"content_block_optional_tag\",\"content_block_video\":\"\",\"_content_block_video\":\"content_block_video\",\"content_media_position\":\"left\",\"_content_media_position\":\"content_media_position\",\"brightcove_account_id\":\"\",\"_brightcove_account_id\":\"bright_cove_account_id\"},\"mode\":\"edit\",\"className\":\"mt-2 mb-2\"} \/-->\n\n<!-- wp:acf\/featured-banner-block {\"name\":\"acf\/featured-banner-block\",\"data\":{\"mco_featured_banner_negative\":\"1\",\"_mco_featured_banner_negative\":\"mco_featured_banner_negative_294ytohe\",\"image\":3653216,\"_image\":\"mco_featured_banner_block_image\",\"title\":\"Advance your R\\u0026amp;D career with us\",\"_title\":\"mco_featured_banner_block_title\",\"description\":\"We\u2019re looking for world-class scientists to join our R\\u0026amp;D team who are passionate about making a difference for patients.\",\"_description\":\"mco_featured_banner_block_description\",\"content_label\":\"\",\"_content_label\":\"mco_featured_banner_block_content_label\",\"cta_one\":{\"title\":\"Explore the possibilities\",\"url\":\"https:\/\/jobs.merck.com\/us\/en\",\"target\":\"\"},\"_cta_one\":\"mco_featured_banner_block_cta_one\",\"cta_two\":\"\",\"_cta_two\":\"mco_featured_banner_block_cta_two\",\"cta_three\":\"\",\"_cta_three\":\"mco_featured_banner_block_cta_three\"},\"mode\":\"edit\",\"className\":\"mb-2 mt-2\"} \/-->","post_title":"Discovery &amp; development","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"discovery-development","to_ping":"","pinged":"","post_modified":"2025-08-06 07:47:20","post_modified_gmt":"2025-08-06 11:47:20","post_content_filtered":"","post_parent":47,"guid":"https:\/\/vip2-msd.com\/merckcom-migrated\/?page_id=244313","menu_order":3,"post_type":"page","post_mime_type":"","comment_count":"0","filter":"raw"},"subheader_title":"Learn more about how to monitor your skin for melanoma and ways to help prevent it","secondary_image":false,"video_hosting_selection":"youtube","youtube_url":"","primary_cta":"Read more","secondary_cta":""}},"_links":{"self":[{"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/story\/3663350","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/story"}],"about":[{"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/types\/story"}],"version-history":[{"count":27,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/story\/3663350\/revisions"}],"predecessor-version":[{"id":3666197,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/story\/3663350\/revisions\/3666197"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/media\/3665655"}],"wp:attachment":[{"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/media?parent=3663350"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/tags?post=3663350"},{"taxonomy":"content_topic","embeddable":true,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/content_topic?post=3663350"},{"taxonomy":"Admin Field","embeddable":true,"href":"https:\/\/vip2-msd.com\/merckcom-migrated\/wp-json\/wp\/v2\/admin_field?post=3663350"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}